Children: A prescription cannabidiol product (Epidiolex) is POSSIBLY SAFE when taken by mouth daily. The most common dose used is 10 mg/kg daily. Higher doses of 15-20 mg/kg daily may be used in some children, but these higher doses are more likely to cause side effects. This product is approved for use in certain children 2 years of age and older, but has been used in children as young as 1 year of age.
There are 33 states with laws specifically regulating Hemp to include: Alabama, California, Colorado, Connecticut, Delaware, Florida, Hawaii, Illinois, Indiana, Kentucky, Maine, Maryland, Michigan, Minnesota, Missouri, Montana, Nebraska, Nevada, New Hampshire, New York, North Carolina, North Dakota, Oregon, Pennsylvania, Rhode Island, South Carolina, Tennessee, Utah, Vermont, Virginia, Washington, and West Virginia.
In general, the majority of people end up using higher-strength products for pain than they would for things like anxiety, stress, or depression. The majority of today’s best CBD oil manufacturers offer tinctures in three different “potencies,” usually in 100, 300, or 600 mg options. Many people start on a middle ground with a 300 mg option, and work your way up from there, but it is extremely important to consult with the brand you are purchasing from before consumption.
Children: A prescription cannabidiol product (Epidiolex) is POSSIBLY SAFE when taken by mouth daily. The most common dose used is 10 mg/kg daily. Higher doses of 15-20 mg/kg daily may be used in some children, but these higher doses are more likely to cause side effects. This product is approved for use in certain children 2 years of age and older, but has been used in children as young as 1 year of age.
people don’t use CBD for recreational use. it has little to no THC so has no psychoactive properties. many CBD products processed from hemp also do not have enough CBD to affect any medical disorders either. they are just jumping on the trendy CBD bandwagon, like many other so-called “nutritional supplements”. so it is very difficult to find and trust the CBD processed form hemp. useful CBD from hemp can only be processed from the flowers, which is still illegal, even though no THC. the only legal use of hemp in the states is for “industrial” use, only the stalks and seeds (fiber and oil). the stalks and seeds of hemp are so lacking in usable CBD that it is not legitimate for medical use.
Green Gorilla marks itself out by simply blending its flagship line of CBD oils with organically produced extra virgin olive oil – and nothing else. And, as the company states, there’s a benefit to this beyond assuring the product’s purity. In particular, olive oil “has synergistic effects in combination with CBD,” and according to Green Gorilla’s website, it’s “also able to deliver the CBD to the parts of [the] body that need it most.” The products are certainly affordable, too: its 150 mg pure CBD oil comes in at $25.99, for instance, making it a smart choice for new users. And anyone still uncertain about the potential effects of Green Gorilla’s products may have their questions answered by the convenient “science” section of the manufacturer’s website, which neatly explains the difference between THC – the cannabinoid that makes people “high” – and CBD.
As of May 2017, however, you will find the addition of "Marihuana Extract" in the Texas Register [PDF] (not the Health and Safety Code) by the order [PDF] of the Commissioner of the Department of State Health Services. That order is what the Tarrant County District Attorney is using as a basis to prosecute CBD oil possession cases at the misdemeanor level. 
If your intention is to help treat chronic pain, then you may want to start out with a lower dose, and then proceed from there. If you notice effective results, you can downsize the dose, or likewise you can always up the dose until positive results are achieved. The key is to only increase your dosage in small increments so that you are able to pinpoint exactly how much CBD oil it takes to treat your condition. Be advised, though, that you should not exceed the recommended daily doses that are listed on the bottle and you should consult with a physician.
After two decades of experience in the hemp industry, Paul Benhaim founded Elixinol – ostensibly, as the company’s website states, to “[manufacture] and [provide] the highest-quality CBD oil and hemp extracts in the world.” And so that CBD oil users can be assured of that quality, Elixinol extensively tests its extracts and provides certificates of analysis for its products that are available to view at a click. The manufacturer’s wares have even received a “stamp of approval” from The Realm of Caring Foundation, a Colorado-based non-profit and advocate for cannabinoid therapy research and education. Those wanting to assess Elixinol’s extracts for themselves can choose from its range of oral tinctures – with potencies of 300 mg, 600 mg and 3,600 mg – as well as topical balms and capsules. Plus, the company gives 5 percent of the proceeds from every sale to charity – so buyers may not only feel good after their purchases, but they’ll do some good, too.
Majority of cannabinoids have been shown to have positive effects on the immune system, particularly the CBD oil, as it helps regulate over-active immune systems. This basically means less susceptibility to various kinds of allergens. Moreover, since CBD oil contains a high amount of omega 3 which supports the growth of micro organisms which live in the intestines, it can aid in enhancement of the immune system, and your body will be able to fight flu, illnesses and germs more easily.

There’s plenty of research out there confirming CBD offers relief from a number of health issues. But if you really want to know whether it can help you, there’s an easier way: ask someone that’s tried it. Genuine, real-life users are reporting how CBD has given them the best sleep in years, relieved their anxiety and significantly alleviated their joint and muscle pain. Other candid reviewers report how CBD topicals leave them feeling renewed and radiated. For fresh insights into CBD’s multiple benefits, check out these testimonials for reliable and definitive proof.


In addition to an unflavored option, the drops also come in peppermint and goji berry flavors that are perfect for mixing with beverages. The nutritional information for all three flavors is found on the PlusCBD Oil website. The drops are fairly inexpensive, priced at $0.15 per mg or lower depending on the concentration. The brand offers fast shipping throughout the U.S. and to a wide range of international destinations.

Elixinol has a wide range of products, but their CBD Tincture does the trick. It’s the cream of the crop regarding CBD oils and that reflects in its price. One dropper (1mg) from the 300 series contains 10mg of CBD. This allows you to get precise amounts of CBD and no guess work is required. Elixinol has received numerous awards for their products and extraction process.
In 2018, The Food and Drug Administration (FDA) approved the first CBD-based medication after years of research suggesting that CBD is beneficial to treat two rare and severe forms of childhood epilepsy. The FDA Commissioner Scott Gottlieb has said the approval was “a reminder that advancing sound development programs that properly evaluate active ingredients contained in marijuana can lead to important medical therapies.” He noted that the action was “not an approval of marijuana or all of its components” but rather of one specific CBD medication for a particular use. In April, an advisory committee unanimously recommended approval of the drug for the two types of epilepsy. FDA CBD rules approving hemp as medicine have helped spread awareness about CBD and acceptance regarding its use.
This review paper on the safety and side effects of cannabidiol by the NCBI, for example, suggests that controlled cannabidiol administration is safe and non-toxic in humans and animals. It also does not induce changes in food intake, nor does it affect physiological parameters like heart rate, body temperature or blood pressure. Also, according to this review paper, “high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans.”
Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.
Other potential side effects include low blood pressure, lightheadedness, and drowsiness, but these have typically only occurred in patients who have exceeded doses of 1,500 mg daily for a period of 4 weeks or more; far more than the average person will need take on a daily basis for chronic pain symptoms. (In fact, the majority of CBD users claim they find an effective dose to be anywhere between 10 and 40 mg daily).
Hemp producers who sell CBD products will often use the 2014 Farm Bill to claim that it is legal. This bill includes a provision that allows for the legal cultivation of hemp provided it is used for academic agricultural research or under a state pilot program. But there is still confusion about whether the legal allowance for cultivation also includes selling it.
Online Retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
For epilepsy: A prescription cannabidiol product (Epidiolex) has been used. The recommended starting dose is usually 2.5 mg/kg twice daily (5 mg/kg/day). After one week the dose can be increased to 5 mg/kg twice daily (10 mg/kg/day). If the person doesn't respond to this dose, the maximum recommended is 10 mg/kg twice daily (20 mg/kg/day). In some research, higher doses of up to 50 mg/kg daily have been used. There is no strong scientific evidence that nonprescription cannabidiol products are beneficial for epilepsy.
If you just don’t have the time or inclination to take supplements every day, but you still want to experience the potential benefits of CBD, this Hemp Oil CBD Patch from Pure Ratios could be just what you’re looking for. With little fuss or need for specialist know-how or equipment, simply apply a patch to the target area and enjoy a slow-release 40-mg serving of CBD that will last for up to 96 hours.
This is the second time Moon Mother Hemp Company has placed among the top five brands on our ranking. The Colorado-based company, which was founded about a year ago, sets the bar very high for quality (including USDA-certified organic hemp) without charging the moon for its products. Their tinctures taste so good, you may be sad you don’t need more.  
The CBD oil in everything that’s sold by Receptra Naturals is extracted from hemp from family-owned farms in Colorado. And the oil produced by the hemp plants – which are cultivated completely organically – is only taken from the flowering parts to ensure its purity and quality. Those of an environmentally conscious bent may therefore particularly appreciate the company’s offerings, which include CBD oil blends that aim either to boost users’ overall sense of health or, for people who are particularly physically active, to just give them a bit more pep in their steps. The most potent of these oils is, for the record, a 4,000 mg concentrate. But Receptra Naturals’ range also includes a topical cream, a skin-conditioning body butter and a CBD extract blend for pets that, the producer states, may help with anxiety, mobility and digestion in animals.
Multiple sclerosis (MS). A prescription-only nasal spray product (Sativex, GW Pharmaceuticals) containing both 9-delta-tetrahydrocannabinol (THC) and cannabidiol has been shown to be effective for improving pain, muscle-tightness, and urination frequency in people with MS. This product is used in over 25 countries outside of the United States. But there is inconsistent evidence on the effectiveness of cannabidiol for symptoms of multiple sclerosis when it is used alone. Some early research suggests that using a cannabidiol spray under the tongue might improve pain and muscle tightness, but not muscle spasms, tiredness, bladder control, mobility, or well-being and quality of life in patients with MS.
Seizure disorder (epilepsy). A specific cannabidiol product (Epidiolex, GW Pharmaceuticals) has been shown to reduce seizures in adults and children with various conditions that are linked with seizures. This product is a prescription drug for treating seizures caused by Dravet syndrome or Lennox-Gastaut syndrome. It has also been shown to reduce seizures in people with tuberous sclerosis complex, Sturge-Weber syndrome, febrile infection-related epilepsy syndrome (FIRES), and specific genetic disorders that cause epileptic encephalopathy. But it's not approved for treating these other types of seizures.
The Texas Controlled Substances Act is codified under Texas Health and Safety Code Chapter 481. Health and Safety Code Section 481.032 says that the Commissioner of State Health Services is to set out what substances are deemed Controlled Substances in Texas under Schedules I through V. Chapter 481.034 retains the right for the legislature to remove substances from the Controlled Substance list.

Acne can have a very devastating impact on certain people. Acne can actually lower one’s self esteem and confidence. The good news is that recent research studies have shown that CBD oil can be a great way of treating acne. A recent research study by Journal of Clinical Investigations revealed that CBD oil helps to in lowering production of sebum which leads to acne. This is because CBD oil decreases the lipid synthesis and the proliferation of sebaceous glands, and also has anti inflammatory effects on the sebaceous glands, therefore delivering a therapeutic agent for treatment of acne.


The Hemp Industries Association, or HIA, is a California-based international non-profit with 74 US agricultural and commercial companies as members. RMH Holdings is a Colorado hemp producer. Centuria Natural Foods launched in 2014 as a hemp food producer. Since then, the company has entered many licensing agreements, including with Hi Brands International, Inc, a subsidiary of former presidential candidate Gary Johnson’s Nevada-based company, Cannabis Sativa, Inc.
If one takes high amounts of CBD, the cannabinoid can temporarily neutralize the activity of P450 enzymes and thus alter the way drugs are metabolized inside the body. This action of CBD can be regarded as a side effect, but it’s not always a negative trait, as the deactivation of P450 enzymes is one of the mechanisms through which CBD neutralizes THC as well.
Acne can have a very devastating impact on certain people. Acne can actually lower one’s self esteem and confidence. The good news is that recent research studies have shown that CBD oil can be a great way of treating acne. A recent research study by Journal of Clinical Investigations revealed that CBD oil helps to in lowering production of sebum which leads to acne. This is because CBD oil decreases the lipid synthesis and the proliferation of sebaceous glands, and also has anti inflammatory effects on the sebaceous glands, therefore delivering a therapeutic agent for treatment of acne.
Since it started becoming popular roughly two years or so ago, the general consensus has always been that since CBD oil from top brands does not contain the psychoactive properties of THC, it is therefore legal. Unfortunately, its legality is much more nuanced because of conflicting federal laws and new court cases. What is clear is that in one of the most recent court decisions on the topic, Hemp Industries Assoc. v. DEA, which came out on April 30, 2018, the US Court of Appeals for the Ninth Circuit found that Section 7606 of the 2014 US Farm Bill (the “Farm Bill”) preempts the Controlled Substances Act (CSA), the federal law which designates marijuana as a Schedule I substance (along with heroin and cocaine) making it illegal to possess or use. This means that when there is conflict between the CSA and the Farm Bill, the Farm Bill wins out.

All this talk about THC lands us nicely in the whole “Full Spectrum vs. Pure Isolate” debate. Once you begin shopping for CBD products, you’ll notice a lot of jargon that gets thrown around without much explanation. Now that we’ve introduced THC into the conversation, we can talk about the difference between, and relative benefits of, Full Spectrum CBD and CBD Isolate (and the lesser-known contender: Broad Spectrum).
Does the use of CBD oil have side effects? CBD is a natural substance, a cannabinoid from the cannabis/hemp plant, whose positive properties on the human organism are not only attributed by scientists and physicians but by people all over the world who have experienced its healing and therapeutic abilities. Even though it is a natural substance and because of the fact that we have our own cannabinoid system (endocannabinoid system), it looks as if it has been created for us, nevertheless the question arises whether CBD has side effects. And if so, which one? Under which circumstances? And at what dose?

Hemp producers who sell CBD products will often use the 2014 Farm Bill to claim that it is legal. This bill includes a provision that allows for the legal cultivation of hemp provided it is used for academic agricultural research or under a state pilot program. But there is still confusion about whether the legal allowance for cultivation also includes selling it.
A newcomer to our CBD oils ranking, RE: Botanicals is no stranger to hemp. Founded by John Roulac, a long-time hemp advocate and founder of the organic superfoods brand Nutiva, RE: Botanicals is one of the only CBD brands to earn the USDA organic seal. They deserve a shout-out for prioritizing regenerative agriculture, while keeping prices reasonable.   
Even though CBD federal law now allows for cannabidiol to be used nationwide, it is critical that when purchasing CBD products that you buy products from reputable sources such as American Hemp Oil. Why? Because all our CBD products are made with extracts obtained from industrial hemp ensuring American Hemp Oil products comply with all legal regulations.
Since it started becoming popular roughly two years or so ago, the general consensus has always been that since CBD oil from top brands does not contain the psychoactive properties of THC, it is therefore legal. Unfortunately, its legality is much more nuanced because of conflicting federal laws and new court cases. What is clear is that in one of the most recent court decisions on the topic, Hemp Industries Assoc. v. DEA, which came out on April 30, 2018, the US Court of Appeals for the Ninth Circuit found that Section 7606 of the 2014 US Farm Bill (the “Farm Bill”) preempts the Controlled Substances Act (CSA), the federal law which designates marijuana as a Schedule I substance (along with heroin and cocaine) making it illegal to possess or use. This means that when there is conflict between the CSA and the Farm Bill, the Farm Bill wins out.
Martin Lee, co-founder of Project CBD, told Leafly that hemp fiber and seed contain no usable amounts of cannabinoids. “Cannabidiol can’t be pressed or extracted from hempseed,” he writes. “CBD can be extracted from the flower, leaves, and, only to a very minor extent, from the stalk of the hemp plant. Hemp oil start-ups lack credibility when they say their CBD comes from hempseed and stalk.”
Some additional positive news happened in June 2018, the Food and Drug Administration approved the first CBD-derived drug — Epidiolex, which contains purified CBD — to treat certain childhood seizure syndromes. Very promising findings and many are interested in long term effects. It’s likely that CBD will be used to treat other medical conditions in the near future.
However, like we just mentioned CBD oil for pain management that has been sourced from industrial hemp grown under the farm bill is in fact legal to buy and sell. The best CBD oil brands that we cover here on this site, claim to extract their concentrates from U.S.-based industrial hemp supplies, which if true, are 100% legal since they contain negligible amounts of THC.

When their doctor switched them to a highly purified CBD-only oil, these symptoms immediately disappeared, and their epilepsy remained controlled. A takeaway from this study, and other research suggesting that up to one in five CBD oil products could be contaminated with detectable amounts of THC, is that side effects from over the counter CBD oil products might not actually be due to the chemical action of CBD.


The passing of SB 218 through the Kentucky legislature created a new subsection of KRS 260.850m to 260.289, in which the Industrial Hemp Advisory Board outlines the purpose of an industrial hemp research program, establish license provisions, and create new requirements and license application procedures. This state’s approach is for the potential medical and industrial applications.
Taking CBD orally or vaping it is a great way to address a number of health issues, including sleeplessness, chronic pain and anxiety. But there’s another way to benefit from the power of CBD: topically. There are many topical applications available, including balms, salves, lotions and oils. They will help soothe your skin, calm your nerves, relax your mind and leave you feeling radiant. Warning: due to their popularity, CBD topicals are flooding the market. Finding the best products for your needs can be daunting. This top ten list will get you started.
There are 33 states with laws specifically regulating Hemp to include: Alabama, California, Colorado, Connecticut, Delaware, Florida, Hawaii, Illinois, Indiana, Kentucky, Maine, Maryland, Michigan, Minnesota, Missouri, Montana, Nebraska, Nevada, New Hampshire, New York, North Carolina, North Dakota, Oregon, Pennsylvania, Rhode Island, South Carolina, Tennessee, Utah, Vermont, Virginia, Washington, and West Virginia.
Our Best Value pick is CBDistillery, which offers a full spectrum CBD oil containing naturally occurring cannabinoids and terpenes, along with fatty acid Omega 3, B complex vitamins, and 20 essential amino acids. The oil is derived from non-GMO, U.S.-grown hemp. It also contains trace amounts of fractionated coconut oil for subtle flavoring. All product information and third-party testing results are found on the official CBDistillery product page.
×