CBD shows promise in the treatment of anxiety disorders, according to a report published in the journal Neurotherapeutics in 2015. Looking at results from experimental research, clinical trials, and epidemiological studies, the report’s authors found evidence that CBD may help treat generalized anxiety disorder, panic disorder, social anxiety disorder, obsessive-compulsive disorder, and post-traumatic stress disorder. However, the authors caution that human-based research on CBD and anxiety is fairly limited at this point.
Online Retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
Several CBD manufacturers would not speak on the record for fear of inviting federal retaliation, but said they’ve recently had trouble selling their products to non-cannabis retail stores. In January, the Seattle Central Co-op pulled CBD products from its shelves in reaction to the DEA rule. Meanwhile, CBD remains available online and at many retail health stores across the nation.
Non-THC CBD oils can be highly effective, and are suitable for employees who face random or routine drug tests. Our top pick for this category is the Medterra CBD Oil Tincture, which contains 99.6% CBD and MCT oil (also known as coconut oil extract) without any traces of THC. The oil is derived from hemp plants that are free of GMOs and pesticides, as well. All third-party testing results for the oil are accessible through Medterra’s official product page.
Cannabis oil and CBD have similarities but some important differences for users. Both are cannabinoids that can be found in all cannabis plants including hemp and marijuana. Cannabinoids are the substances secreted by the flowers of the cannabis plant and contain natural medicinal properties, offering relief from conditions including anxiety, pain, nausea, and inflammation.
Some additional positive news happened in June 2018, the Food and Drug Administration approved the first CBD-derived drug — Epidiolex, which contains purified CBD — to treat certain childhood seizure syndromes. Very promising findings and many are interested in long term effects. It’s likely that CBD will be used to treat other medical conditions in the near future.
Way, John. It’s amazing how life can be running along great one day, you’re bothering no one, loving others, minding your own business, enjoying your work and then one crooked cop can railroad you. This cop who screwed me over–Robert Bifano– failed to arrest a suicidal AWOL soldier a few years ago and the guy went on to kill his wife and then shot himself. Bifano got sued for his ineptitude.
Amendment 64 granted Colorado citizens the use and regulation of marijuana. Passed on November 6, 2012, it included a declaration industrial hemp should be regulated separately from marijuana and that the Colorado General Assembly is “to enact legislation governing the cultivation, processing, and sale of industrial hemp.” Soon after Amendment 64 went into effect, Colorado became the first state to contain certified hemp seed – designated as containing less than .3% THC – as well as free of weeds and disease.
Customer Service: We’ve always received fast, informative responses to our queries about products and practices, but there are definitely customers out there who have not. A quick perusal of reviews shows customers who had issues with unaddressed orders. It’s hard to know exactly what the problem is in these situations, but the company’s strict return policy (seven days for unopened products only) probably doesn’t help. It should be noted that the company has a solid base of very satisfied customers as well.
A report from the American Academy of Pediatrics (AAP) published in the journal Pediatrics cautions pregnant women and nursing mothers to avoid marijuana use due to possible adverse developmental effects to their baby. In a study reviewed for the report, short-term exposure to CBD was found to increase the permeability of the placental barrier, potentially placing the fetus at risk from certain substances.
Pure Hemp Botanicals’ mission statement is “compassion in action” – and it’s a pledge that it aims to adhere to not only through the use of organic hemp and cruelty-free ingredients, but also through its employment practices. The company’s “PHD Gives Back” initiative demonstrates a commitment to kindness, too, as 1 percent of proceeds from the sale of its products are donated to non-profit Mercy For Animals. Pure Hemp Botanicals’ range of CBD-containing goods is also varied, taking in as it does concentrates, vape oils and flavored mints and teas. And regular CBD oil users can, furthermore, take advantage of the company’s handy subscription system for tinctures, capsules and softgels – a scheme that’s not only convenient but which, thanks to the discounts available, offers a less costly way to get a CBD hit.
This review paper on the safety and side effects of cannabidiol by the NCBI, for example, suggests that controlled cannabidiol administration is safe and non-toxic in humans and animals. It also does not induce changes in food intake, nor does it affect physiological parameters like heart rate, body temperature or blood pressure. Also, according to this review paper, “high doses up to 1,500 mg/day of CBD are reportedly well tolerated in humans.”
The human body also produces cannabinoids, known as endocannabinoids, in a bodily system known as the endocannabinoid system (or ECS). The ECS promotes homeostasis by regulating a wide range of functions, including motor skills, mood, appetite, and sleep. As we age, our ECS produces fewer endocannabinoids; they may also decrease due to physical injury or disease. Replenishing depleted endocannabinoids with phytocannabinoids like CBD can help restore balance to the body.

This is exciting for many, but also complicated due to the fact that possession of marijuana is still considered a criminal offense at the federal law level. Flying across and transporting marijuana across state lines, drug tests for employees following a visit to one of the states where marijuana is legal and other complications have led many to avoid the topic – and consumption – altogether.
As of early 2017, 14 of these regulated 33 states legally produce hemp seeds. The federal designation indicated hemp could be grown for industrial or academic applications. These 14 states (CA, CO, IN, KY, MA, MO, ND, OR, SC, TN, VT, VA, NC and WV) are producing hemp seeds for industrial use. While regulations and agricultural standards are still developing in America, European sourced is still the ideal choice for the consumers. Ideal conditions, more experience, and refinement of regulations to ensure safety and quality lend more trust to you, our consumer. 
If your intention is to help treat chronic pain, then you may want to start out with a lower dose, and then proceed from there. If you notice effective results, you can downsize the dose, or likewise you can always up the dose until positive results are achieved. The key is to only increase your dosage in small increments so that you are able to pinpoint exactly how much CBD oil it takes to treat your condition. Be advised, though, that you should not exceed the recommended daily doses that are listed on the bottle and you should consult with a physician.

To obtain the CBD-packed hemp extract from its organic crop, Highland Pharms uses a process called “supercritical CO2 extraction.” This method eliminates the need for more harmful solvents, while it also, the company says, yields CBD oil of an outstanding purity and efficacy. Those wanting to see for themselves can take their pick from Highland Pharms’ positively reviewed variety of tinctures – the strongest concentration of which measures up at 1,250 mg – as well as capsules and edibles. And if those potential customers have no idea exactly how much CBD they should be imbibing, then they can get themselves up to speed at the Texas-based company’s website, which offers a user-friendly guide to serving sizes and methods of CBD oil intake, among other common queries.


CBD derived from marijuana is a different story, and the law varies from state to state. But as long as you’re using CBD oil that contains less than 0.3 percent THC, you have nothing to be concerned about anywhere in the United States. On the other hand, if you want to take your CBD on a trip outside the country, definitely look into local laws to avoid getting into awkward situations while you’re away.
Chronic Pain: The body’s ECS plays a role in alleviating and managing pain, so CBD oil can work as a supplement for individuals with medical conditions that cause chronic pain, such as arthritis and multiple sclerosis. CBD oil also increases levels of adenosine in the brain; adenosine is a neurotransmitter that aids cardiovascular function and eases painful inflammation.

A few years ago it was still believed that CBD has no side effects. Well, at least no negative ones, because CBD works in many ways and the side effects that it had were always good ones. In the sense of, “I use CBD for something specific and as a side effect it also helps with something else. But over the years of studies (though there are still too few of them) and experience, a few side effects have been identified. But do not worry, these are not life-threatening side effects. Now let’s look at the toxicity of CBD, the possible side effects, and the safety of CBD.


Serving size can vary based on the product you choose and the CBD concentrations in that product, as well as your own metabolism. Edibles generally have longer lasting effects, but they also take longer to process as they have to go through your entire digestive system, which also breaks down some of that CBD. Edibles such as gummies or capsules are a foolproof way to ensure accurate and consistent serving sizes. CBD that is smoked or vaped acts faster and has less breakdown while also lasting less time overall.
Schizophrenia. Research on the use of cannabidiol for psychotic symptoms in people with schizophrenia is conflicting. Some early research suggests that taking cannabidiol four times daily for 4 weeks improves psychotic symptoms and might be as effective as the antipsychotic medication amisulpride. However, other early research suggests that taking cannabidiol for 14 days is not beneficial. The conflicting results might be related to the cannabidiol dose used and duration of treatment.
Multiple sclerosis (MS). A prescription-only nasal spray product (Sativex, GW Pharmaceuticals) containing both 9-delta-tetrahydrocannabinol (THC) and cannabidiol has been shown to be effective for improving pain, muscle-tightness, and urination frequency in people with MS. This product is used in over 25 countries outside of the United States. But there is inconsistent evidence on the effectiveness of cannabidiol for symptoms of multiple sclerosis when it is used alone. Some early research suggests that using a cannabidiol spray under the tongue might improve pain and muscle tightness, but not muscle spasms, tiredness, bladder control, mobility, or well-being and quality of life in patients with MS.
CBD plays a major role in the immune system modulation which basically means that it helps in auto-immune conditions such as rheumatoid arthritis. Rheumatoid arthritis is a chronic progressive disease which causes inflammation in joints, resulting in painful deformity, and at times immobility in the fingers, feet, wrists, and ankles. Because to it’s anti inflammatory effects, CBD oil provides relief of joint pain caused by rheumatoid arthritis, and can also decrease joint destruction.
At the top of our ranking is Portland-based Lazarus Naturals, which has honed a reputation for high-quality, affordable CBD. Their consciously crafted CBD is sourced from organic, Oregon-grown hemp which the company controls from seed to sale. With low prices, a robust assistance program, free shipping, and a 30-day, no questions asked return policy, you really can’t go wrong with Lazarus Naturals.
Dry Mouth: As is the case with many other hemp- and marijuana-based products, CBD oil often leads to a condition known as dry mouth (or cottonmouth). This is likely due to cannabinoids altering receptors in the lower jaw that trigger salivation. In most cases, mild discomfort and stronger-than-average thirst are the only issues associated with dry mouth.
These are one of the most popular (and effective) choices for arthritis and other forms of localized pain and inflammation. Since the skin acts as an excellent semi-permeable membrane that “let’s the good stuff and keeps the bad stuff out,” rubbing CBD-infused creams into the affected area has proved to be quite effective in terms of both pain and inflammation reduction.
A condition in which a transplant attacks the body (graft-versus-host disease or GVHD). Graft-versus-host disease is a complication that can occur after a bone marrow transplant. In people with this condition, donor cells attack the person's own cells. Early research shows that taking cannabidiol daily starting 7 days before bone marrow transplant and continuing for 30 days after transplant can extend the time it takes for a person to develop GVHD.
Kat’s Naturals not only takes the quality of its products seriously, but it also ensures that their contents are produced in a way that’s as environmentally friendly as possible. The essential oils in its best-selling Heal CBD Hemp Oil, for example, are harvested in a sustainable manner, while the hemp that goes into its range more generally is completely organically grown. And in a customer-friendly move, Kat’s Naturals provides CBD oil blends specifically tailored to users’ needs, whether they want to boost metabolism, get a good night’s rest or simply feel freer from muscle pain. Perhaps the most innovative Kat’s Naturals product, though, is its CBD-containing capsaicin cream. This topical owes its heat in part to a component commonly found within chili peppers, and the company’s website claims that it also helps give respite to neuropathy sufferers and those with Raynaud syndrome.

Disclaimer: This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.
Pioneers of the CBD industry, 4 Corners Cannabis helped pave the way for companies that want to provide quality products and utilize best practices. They grow their own strain of hemp and make small batches of true full-spectrum CBD products. Their prices place them lower down on our ranking, but their highly satisfied customers are more than willing to pay for the 4 Corners quality.  
As of early 2017, 14 of these regulated 33 states legally produce hemp seeds. The federal designation indicated hemp could be grown for industrial or academic applications. These 14 states (CA, CO, IN, KY, MA, MO, ND, OR, SC, TN, VT, VA, NC and WV) are producing hemp seeds for industrial use. While regulations and agricultural standards are still developing in America, European sourced is still the ideal choice for the consumers. Ideal conditions, more experience, and refinement of regulations to ensure safety and quality lend more trust to you, our consumer. 

Disclaimer: *The information below and any other communication regarding legality which you may receive from any representative of Green Roads or the Green Roads’ website is for informational purposes only and not for the purpose of providing legal advice. You must make your own judgment regarding whether you should purchase CBD in your jurisdiction. You should contact your attorney to obtain more specific guidance.*
A report from the American Academy of Pediatrics (AAP) published in the journal Pediatrics cautions pregnant women and nursing mothers to avoid marijuana use due to possible adverse developmental effects to their baby. In a study reviewed for the report, short-term exposure to CBD was found to increase the permeability of the placental barrier, potentially placing the fetus at risk from certain substances.
THC is found in large quantities in cannabis, or what most people think of as the marijuana plant. Unlike cannabis, or marijuana, hemp contains low concentrations of THC. CBD Oils are generally made from the hemp plant so they contain high levels of CBD and trace levels of THC. As a result, CBD provides a less controversial alternative to THC for health benefits.

Disclaimer: This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A Doctor's advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Individual weight loss results will vary. By using this site, you agree to follow the Privacy Policy and all Terms & Conditions printed on this site. Void Where Prohibited by Law.


CBD derived from marijuana is a different story, and the law varies from state to state. But as long as you’re using CBD oil that contains less than 0.3 percent THC, you have nothing to be concerned about anywhere in the United States. On the other hand, if you want to take your CBD on a trip outside the country, definitely look into local laws to avoid getting into awkward situations while you’re away.
As mentioned above, CBD is no longer considered a Schedule I controlled substance under the Farm Act. However, under the DEA’s definition, it remains on the list. This allows for individual states to create exceptions to the status of CBD, even when cultivated from hemp plants grown legally under the act. It also maintains illegal status for any CBD sourced from plants produced in settings that are not consistent with that Act, or by an unlicensed grower. It is expected that more clarification on the status of CBD will come early this year (2019).
Californians also have to take into consideration Prop 65. This proposition requires that businesses refrain from knowingly and intentionally exposing individuals to any of the chemicals contained in a state-published list of chemicals which are known to cause cancer or reproductive harm. This, among many other factors, is why HempMeds adheres to the Triple Lab Tested® Standard. We believe in a common sense approach where safety and knowing what goes into your body is of utmost importance.
Cannabidiol has antipsychotic effects. The exact cause for these effects is not clear. But cannabidiol seems to prevent the breakdown of a chemical in the brain that affects pain, mood, and mental function. Preventing the breakdown of this chemical and increasing its levels in the blood seems to reduce psychotic symptoms associated with conditions such as schizophrenia. Cannabidiol might also block some of the psychoactive effects of delta-9-tetrahydrocannabinol (THC). Also, cannabidiol seems to reduce pain and anxiety.
Once extracted from the stalks and seeds of hemp, pure CBD hemp oil can be taken directly or infused into products like tinctures, liquids, capsules, and topicals. With demand for high-CBD hemp oil now higher than ever, there are a wide variety of CBD hemp oil products available for purchase at retailers or online with delivery straight to your door.
No. As of August 2017, possessing THC oil is not only a crime but also considered a more serious crime than possessing marijuana in its traditional form. In Texas, it is a felony to possess THC oil or wax. The seriousness of the felony varies based on the amount of THC oil possessed. For example, possession of less than one gram of THC oil is a state jail felony that is punishable by six months to two years in a state jail facility and a fine of up to $10,000.
NuRyse Hemp Oil Extract 1000mg includes a 1-year money back guarantee, which is unique when compared to other hemp oil products on the market. In addition, NuRyse Hemp Oil Extract is made in the USA, is flavored and formulated with all-natural ingredients, and is available in varying levels of potency (250mg and 500mg in addition to the 1000mg bottle). It is a hemp seed oil product, however, so it will not contain the CBD cannabinoid. Each bottle contains the standard 30-day supply with recommended dosage.
Statement from FDA Commissioner Scot Gottlieb, M.D., on signing of the Agriculture Improvement Act and the agency's regulation of products containing cannabis and cannabis-derived compounds. U.S. Food and Drug Administration Web site. Available at: https://www.fda.gov/news-events/press-announcements/statement-fda-commissioner-scott-gottlieb-md-signing-agriculture-improvement-act-and-agencys. (Accessed May 7, 2019).
President Obama’s execution of the Agricultural Act of 2014 is an integral piece to CBD oil’s legality. If a plant is deemed legal (where the determining factor is a THC level under .3%) that then makes all products made from the source material legal as well. Did you ever wonder why your hemp lotion 15-20 years ago was legal but “smoking a little weed” wasn’t? In this case, it’s all about the THC levels your plant doesn’t have.
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